We suggest that IL-1α release from infundibular keratinocyte in response to P. acnes-mediated TLR activation is an important step in the complex natural history of the acne lesion (Figure 4). Moreover ...

Introduction Approximately 30-50% of patients with cancer experience pain at the time of diagnosis, and about 75-95% experience pain in the terminal phase of the illness. [1] Among the different types ...

Conclusions The present work highlights the remarkable convergence of schizophrenia negative symptomatology and autistic features. It shows that the PAUSS correlates substantially with the ADOS.

A conceptual model of interactions between families, clinicians, and ICU determinants influencing goal-directed care for infants and children with chronic critical illness. *Adapted from Kelley et al ...

Bioidentical or plant-derived hormones have uncertain efficacy or safety in treating menopausal symptoms. What is the evidence supporting the use of compounded and FDA-approved bioidentical products?

Management of NK-cell Malignancies The appropriate therapeutic approach for NK-cell malignancies should be determined according to the following clinical subtypes: nasal NK-cell lymphoma, non-nasal NK ...

The National Institutes of Health Stroke Scale (NIHSS) is accepted as the definitive clinical examination to assess stroke severity. This project examined barriers to implementation and NIHSS use by ...

Pediatric penetrating keratoplasty is technically more challenging than adult keratoplasty because of a smaller anatomical configuration, reduced rigidity and increased elasticity of the cornea and ...

Language Assessment The Mini-Mental State Examination (MMSE) [12] does allow some formal testing of language, but additional detailed testing is required to gain insight into the type of underlying ...

The development of PH is common in COPD, with the incidence of PH and right ventricular hypertrophy in COPD patients older than 50 years observed to be at least 50%. Severe PH complicating COPD is a ...