The Arizona Cardinals delivered the dominant offensive performance fans have been craving against the San Francisco 49ers.

Despite entering their season finale on Sunday having lost five of their previous six games, the Arizona Cardinals had a ...

San Francisco 49ers running back Isaac Guerendo was carted off the field in the first quarter against the Arizona Cardinals.

Trey McBride and the Arizona Cardinals will host George Kittle and the San Francisco 49ers on Sunday at 4:25 p.m. ET, in a ...

The Miami Dolphins are set to own the No. 13 pick in the 2025 NFL draft. After losing Sunday against the New York Jets, the ...

Kyler Murray threw for 242 yards and four touchdowns, two to Greg Dortch, and the Arizona Cardinals beat the injury-depleted ...

The Mount Union and North Central college football teams meet in the Amos Alonzo Stagg Bowl. Get live NCAA D3 title game ...

The Cardinals earned the No. 16 overall pick in the first round of the 2025 NFL Draft after their season ended with a win ...

Jennings got into fights on consecutive plays and fell 25 yards short of a career milestone. But he didn't seem to mind.

Check out Kyler Murray's postgame interview after the Arizona Cardinals defeated the San Francisco 49ers in the last game of the regular season.

The Arizona Cardinals enter the offseason coming off a victory, as they defeated the San Francisco 49ers on Sunday. Here are ...

GLENDALE -- San Francisco 49ers RB Isaac Guerendo was carted off the field in Week 18's matchup against the Arizona Cardinals. He has already been ruled out with a knee and ankle injury. On just the ...