The 49ers have had success drafting defensive players on day three of the draft. In recent years under John Lynch, the 49ers have drafted players like Malik Mustapha, Dee Winters, Deommodore Lenoir and Dre Greenlaw on day three of the draft.

Pro Football Network contributor Marco Enriquez released his latest mock draft, projecting the San Francisco 49ers to strengthen their defensive backfield with the 11th overall pick.

The most important choice the San Francisco 49ers will make is with the 10 selections they are scheduled to have in the 2025 NFL Draft, including the 11th overall pick.

San Francisco is projected to land four comp picks, and their seventh-round choice via the Panthers came in a trade last year that landed kicker Zane Gonzalez with the 49ers. It’s unclear what the conditions of the pick swap were, so there’s a chance San Francisco actually holds onto its own pick, which is slated for No. 229.

Following a disappointing 6-11 season, the 49ers are uniquely positioned for a quick bounce-back, especially if they can get a second-straight quality draft class. After years of

In the latest 2025 NFL mock draft for ESPN, the San Francisco 49ers have a clear direction in which they want to head. ESPN’s Matt Miller shared his latest two-round mock draft following the Senior Bowl and Shrine Bowl all-star events.