Neuroinflammation drives the progression of neurodegenerative disorders like Alzheimer's, Parkinson's, and multiple sclerosis ...

Serendipity is to thank for several ground-breaking discoveries and treatments, such as Alexander Fleming’s accidental discovery of penicillin. 1 However, most drug breakthroughs stem from systematic ...

Malaria represents one of the most serious threats to human health worldwide, and preventing and curing this parasitic disease still depends predominantly on the administration of a small number of ...

Understanding a drug’s mechanism of action (MOA) can greatly increase the likelihood of successful clinical trials by identifying biomarkers of patient response and providing a rationale for ...

More and more bacterial pathogens are developing resistance. There is an increasing risk that common drugs will no longer be effective against infectious diseases. That is why scientists around the ...

Antibody therapeutics are a rapidly growing class of drugs used to treat infections as well as a range of diseases. Among them are cancer and autoimmunity particularly important, and the use of ...

The rise of antimicrobial-resistant pathogens has spurred scientists to search far and wide for new drugs. And while many antimicrobial molecules have been discovered in recent years, it’s rare to ...

Most of the oncology drugs that received the FDA’s accelerated approval from 2011 to 2020 had some kind of FDA postmarketing safety action, according to a research letter. Safety actions included ...