Refining the uncharted landscape of human transcription factors—strategic framework created for future prioritization

The human genome contains approximately 1,600 types of transcription factors responsible for regulating gene activity across ...
News Medical

Role of Transcription Factors

Transcription refers to the creation of a complimentary strand of RNA copied from a DNA sequence. This results in the formation of messenger RNA (mRNA), which is used to synthesize a protein via ...
eLife

The Fd4 transcription factor translates transient spatial cues in progenitors into long-term lineage identity

Institute of Neuroscience, Howard Hughes Medical Institute, University of Oregon, Eugene, United States ...
EurekAlert!

(Epi)genetic aspects of metabolic syndrome pathogenesis in relation to brain-derived neurotrophic factor expression

This is due to epigenetic components: microRNA, histone and DNA methylation, gene mutations that alter the expression and production of the neurotrophic factor BDNF, which interacts with the receptors ...
EurekAlert!

Refining the uncharted landscape of human transcription factors: a strategic framework for future prioritization

Researchers at University of Tsukuba have comprehensively analyzed genomic binding data of transcription factors (proteins that regulate gene expression) in humans, revealing a substantial amount of ...