A large, multi-institution study led by a Brown University physician-scientist could have important implications for the development of new classes of cancer therapeutics.

A hidden “jack-in-the-box” mechanism inside T cells may hold the key to unlocking more powerful cancer immunotherapies.

Scientists have discovered that T cell receptors activate through a hidden spring-like motion that had never been seen before ...

T cell immunotherapies are on the cutting-edge of cancer treatments, but a full understanding of how they work has been ...

A research team has discovered when and why inflammatory signaling affects the formation of blood stem cells in embryos, which will benefit efforts to develop lab-grown, patient-derived stem cell ...

One of the most exciting advances in cancer treatments in the past decade is the development of T cell immunotherapies, in which a patient's own ...

Cell signaling is crucial for cells to communicate and function correctly. Disruptions in these pathways, caused by genetic mutations or environmental factors, can lead to uncontrolled cell growth, ...

From the moment an embryo starts to take shape, two-way communication is critical for making sure tissues and organs develop ...