San Ramón is a municipality in the Matagalpa department of Nicaragua. San Ramon lies 12 kilometers northeast of the departmental capital o…San Ramón is a municipality in the Matagalpa department of Nicaragua. San Ramon lies 12 kilometers northeast of the departmental capital of Matagalpa. The 12-kilometer drive takes about 15 minutes by taxi, 20 minutes by bus. The road is entirely paved.